红花五味子茎低极性化学成分的GC-MS分析
投稿时间:2018-01-21  修订日期:2019-07-08  点此下载全文
引用本文:郑巍,刘晓娟,贾琳,陈海生,郭良君,金永生.红花五味子茎低极性化学成分的GC-MS分析[J].药学实践杂志,2019,37(6):491~494
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作者单位E-mail
郑巍 海军军医大学药学院, 上海 200433
解放军第九八医院药械科, 浙江 湖州 313000 
 
刘晓娟 厦门市医药研究所, 福建 厦门 361003  
贾琳 解放军第四五四医院药学部, 江苏 南京 210000  
陈海生 海军军医大学药学院, 上海 200433  
郭良君 解放军第九八医院药械科, 浙江 湖州 313000 glj201088@aliyun.com 
金永生 海军军医大学药学院, 上海 200433 ysjinsmmu@163.com 
基金项目:国家自然基金资助项目(No.81573585);原南京军区医学创新课题重大项目(No.14ZD02)
中文摘要:目的 研究红花五味子茎低极性部位的主要化学成分。方法 红花五味子茎用90%乙醇热提取,提取液用石油醚萃取得到石油醚部位,运用GC-MS法对其主要成分进行检测,所测结果与标准谱库进行分析,用峰面积归一法计算各个成分的相对含量。结果 鉴定了49种化学成分,相对含量较高的有β-芹子烯,约占12.08%、顺,顺-2-甲基-3,13-十八烯醇,约占10.3%。结论 红花五味子茎低极性部位化学成分主要为酯类化合物(45.94%),其次为脂肪酸(19.35%)和倍半萜(13.94%)。
中文关键词:红花五味子  低极性部位  气质联用  中药化学
 
Analysis of low-polarity components from stems of Schisandra rubriflora (Franch). Rehd.et Wils by GC-MS.
Abstract:Objective To investigate the low-polarity components from the stems of Schisandra rubriflora (Franch).Rehd.et Wils.Methods Dried and grinded stems of this plant were extracted by 90% ethylalcohol,then the extraction was partitioned by petroleum ether to afford petroleum extract,which was analyzed by GC-MS and elucidated by the comparison with the standard mass spectral data.The relative contents in percentage were calculated by the area normalization method.Results 49 compounds were identified.Of them,β-selinene (12.08%),2-methyl-Z,Z-3,13-octadecadienol (10.3%) were the main components.Conclusion The main components in the low-polarity components of the stems of Schisandra rubriflora (Franch).Rehd.et Wils.were esters (45.94%),fatty acids (19.35%) and sesquiterpenoids (13.94%).
keywords:Schisandra rubriflora (Franch)  low-polarity partition  GC-MS  Chinese medicinal chemistry
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